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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 2Bao, H.
- 2Guan, L. L.
- 2Kommadath, A.
- 2Plastow, G. S.
- 2Stothard, P.
- 30Graduate and Postdoctoral Studies (GPS), Faculty of
- 30Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 12Biological Sciences, Department of
- 8Biological Sciences, Department of/BioSci OER
- 4Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 2Roy Berg Kinsella Research Ranch
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The Study of Hereditary Spastic Paraplegia Genes Using Drosophila Homologues: Behavioural Insights
DownloadFall 2014
Hereditary Spastic Paraplegia (HSP) denotes a heterogeneous group of heritable neurodegenerative disorders predominantly characterized by progressive weakness and spasticity of the legs. Mutations in the gene SPAST are by far the most common, while mutations in the gene ATL1 are the second most...
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Transcriptional regulation of von Willebrand Factor gene in response to hypoxia and in cancer cells
DownloadFall 2016
Von Willebrand Factor (VWF) is a pro-coagulant, glycosylated protein that is exclusively expressed in endothelial cells and megakaryocytes. An acute phase protein, VWF is upregulated or released from activated or injured endothelial cells. In addition, it is a carrier for factor VIII that...
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Fall 2014
Fragile X Syndrome (FXS) is the most common genetic cause of Intellectual Disability, affecting 1 in 4000 boys and 1 in 6000 girls. Work in our lab using Drosophila melanogaster and since replicated in the mouse model has shown that excess protein synthesis is a major mechanism connecting the...