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Intracellular expression of Fas Ligand and Granzyme B by tumor infiltrating or in vitro activated CD8+ T cell populations
DownloadSpring 2019
CD8+ T cells can recognize infected or cancerous cells and eliminate them by exocytosing cytolytic molecules or presenting death ligands on their surface, both of which can initiate apoptosis in target cells. Granzyme B (GzmB) and Fas Ligand (FasL) are two of the effector proteins that CD8+ T...
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