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- 1Fecal microbial transplantation
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Effect of Antimicrobial Exposure on Clostridioides difficile (C. difficile) Colonization of the Infant Gut Microbiota in the Canadian Healthy Infant Longitudinal Development (CHILD) Birth Cohort
DownloadSpring 2020
Introduction: Antimicrobial exposure in early life has been associated with gut microbiota dysbiosis and development of allergic diseases in childhood. In adults and older children, C. difficile is the major pathogen responsible for antibiotic-induced diarrhea but the effect of colonization with...
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In silico analysis of changes in predicted metabolic capabilities of intestinal microbiota after fecal microbial transplantation for treatment of recurrent Clostridioides difficile infection
DownloadSpring 2023
Importance: Fecal microbial transplantation (FMT) is effective in treating recurrent Clostridioides difficile (RCDI) infection. The therapeutic efficacy of FMT is thought to be related to restoration of intestinal microbial composition and diversity and key microbially derived compounds, such as...
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The Impact of Maternal Distress on Child Neurodevelopment in a Sex-Specific Manner: Examining the Mediating Role of the Infant Gut Microbiome
DownloadFall 2021
Introduction Depression has taken over as the leading cause of disability worldwide. In Alberta, 7% of mothers reported prenatal depressive symptoms and more than 25% of women worldwide reported mental health-related concerns after childbirth. The DOHaD hypothesis aims to emphasize that both the...