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Skip to Search Results- 2Veldhoen, Richard
- 1Aburahess, Salah
- 1Akuamoah Boateng, Maxwell
- 1Alqahtani,Hind M
- 1Beauchesne, Nicholas L.
- 1Bekele, Raie Taye
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Delineation of Molecular Mechanisms Underlying the Pathobiology of ALK-positive Anaplastic Large-cell Lymphoma
DownloadSpring 2017
ALK-positive anaplastic large-cell lymphoma (ALK+ALCL) is a rare type non-Hodgkin lymphoma of null/T cell original, preferentially occurs in children and young adults. Approximately 85% of ALK+ALCL patients carry the gene translocation t(2;5)(p23;q35), which results in the generation of the...
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Spring 2014
This thesis examines the way gender and race intersect to produce a narrative of Africa as a place in need of development. Combining a theory of intersectionality as the interaction between race, gender, and class with the power relationships represented in and constituted by visual imagery, this...
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Developing an M3 Antagonist for Molecular Imaging of Muscarinic Acetylcholine Receptors in Breast Cancer
DownloadFall 2021
The lack of the three targeted receptors, estrogen, progesterone, and the human epidermal growth factor receptor 2, causes difficulty in treating triple negative type cancers. Most often, patients with this type of malignancy have a low chance of survival. The focus of this work will be on...
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Documenting a Punk Scene in Edmonton, Alberta 1979-1985: Place, Legitimacy and Belonging Articulated Through Mainstream and Independent Media
DownloadSpring 2016
This thesis explores the emergence of a punk music scene in Edmonton, utilizing archival research, participant interviews and analysis of mainstream and independent media to determine how a genre that was arguably considered a British phenomenon came to have local characteristics and...
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Fall 2015
Tumor targeting ligands provide a promising solution to the problems associated with the selective delivery of conventional cancer chemotherapeutics and diagnostics to cancer cells. Therefore, numerous cancer cell surface targeting peptides have been identified and evaluated. These peptides have...
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Establishing the anti-cancer effects of unsaturated fatty acids and a novel oil on human breast cancer cells
DownloadFall 2012
N-3 and n-6 fatty acids and conjugated linoleic (CLA) acid have been known to inhibit breast cancer cell growth, however, effects on normal cells and of single and mixtures of n-3 and n-6 pathway intermediates have not been thoroughly investigated. The objective of this thesis was to determine...
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Fall 2021
Breast cancer is the most common cancer amongst women in Canada. The current treatment regime for early stage breast cancers is breast-conserving surgery with radiation therapy. However, 10-20% of patients develop local recurrence, and some exhibit metastatic spread, which is associated with a...
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Fall 2015
Background: Breast conserving surgery (BCS) followed by radiation is the preferred treatment option for early stage breast cancer because it is less invasive than the alternative treatment, mastectomy, and provides a better cosmetic outcome and a superior quality of life. Positive surgical...
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Fall 2010
Breast cancer is the most common cancer and the leading cause of cancer-related death among Canadian women. Despite improvements in treatment and early detection, there is still a need to develop novel therapies for breast cancer management. Aberrant Notch signaling is tumorigenic and is...
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Fall 2009
Using a recently developed measure of extrinsic contingency focus (ECF; Williams, Schimel, Hayes & Martens, 2009), four studies were conducted to examine the relationship between extrinsic contingency focus and the extent to which individuals strive to meet the social ideals shown in advertising...