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Skip to Search Results- 1Berger, Christopher J.
- 1Bhangu, Jasmine
- 1Endean, Riley Thomas
- 1Hass, Michael J.
- 1Penner, Marlin
- 1Sullivan, Erin Rae
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Fall 2011
In the Introduction of this thesis, consideration is given to historical and ongoing value of investing research efforts in the total synthesis of natural products. Following this discussion is an explanation of the factors that guided the selection of palmerolide A as a synthetic target. The...
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Spring 2021
A thorough overview of esters and their reductions is presented. A large focus was placed on reductions via homogeneous catalytic hydrogenation. Although several ester hydrogenation systems have been developed, the production of highly enantioenriched alcohols has generally relied upon the usage...
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Spring 2011
The Noyori-type catalyst trans-Ru((R)-BINAP)(H)2((R,R)-dpen) (6) and its analogues are among the most active and enantioselective ketone hydrogenation systems reported to date. Its applications towards other types of carbonyl compounds are, however, understudied. This dissertation describes the...
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Fall 2011
Propargylic alcohol natural products are found in many species of terrestrial plants and marine organisms. Because these compounds are usually isolated from the natural source in only small amounts, few studies of propargylic alcohol natural products have been conducted to date. Nevertheless,...
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Lewis Base Adducts of Borafluorene: En Route to Polymers and the Discovery of New Luminescent Adducts
DownloadFall 2013
A series of novel Lewis base monoadducts of 9-bromo-9-borafluorene (BrBFl•LB, LB = IPr, IPrCH2, PPh3) and the bisadduct [(DMAP)2BFl]Br were prepared and underwent reactivity studies in the pursuit of incorporating a borafluorene unit into a polymeric scaffold for the sensing of nucleophiles in...
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Fall 2015
Organic chemistry has its foundations in the 19th century; since, it has grown into a number of industries affecting our daily lives such as the manufacture of goods and life saving pharmaceuticals. The need for new and increasingly efficient synthetic methods has grown in response to the...
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Synthesis, Structure and Properties of a Novel “Frustrated” Benzoxaborole and the Role of Boron in Bioconjugation
DownloadSpring 2020
Chapter 2 describes an optimized 7-step successful synthesis of a first of its kind permanently open-form ortho-hydroxyalkyl arylboronic acid, otherwise known as a “frustrated benzoxaborole”, with a columnless purification and complete structure elucidation. This novel compound is completely...