This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Search
Skip to Search Results-
REGULATION OF THE BMI1 AND RET PROTO-ONCOGENES BY THE DLX2 TRANSCRIPTION FACTOR IN THE DEVELOPING GASTRO-INTESTINAL TRACT
DownloadFall 2017
The Dlx1/Dlx2 double knockout (DKO) mouse dies at P0 with a cleft palate and a distended abdomen. Within the intestinal crypts of Leiberkuhn a stable, non-dividing stem cell group is marked by the oncogene BMI1. Unpublished data from the Eisenstat laboratory demonstrates co-expression of BMI1 and...
-
Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...