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- 1Anbukarasu, Preetam
- 1Arutyunov, Denis
- 1Assempour, Nazanin
- 1Belal, Ahmed S. F.
- 1Boulet, Joel L
- 23Graduate and Postdoctoral Studies (GPS), Faculty of
- 23Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 1Mechanical Engineering, Department of
- 1Mechanical Engineering, Department of/Progress in Canadian Mechanical Engineering, Volume 5
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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Fall 2014
The discovery and subsequent applications of fluorescent proteins (FPs) launched a new era for live cell fluorescence imaging. The design and developments of FP-based indicators have further solidified the versatility of FPs and rendered them as indispensable tools in life science research now...
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Fall 2011
AC Dielectrophoresis, the motion of dielectric colloidal particles in the presence of an inhomogeneous AC electric field, has been utilized in this work as a mechanism for preventing channel wall fouling due to particle deposition for a multi-component colloidal system. Both attractive and...
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Spring 2013
The sources of inducing field gradients and their implications are investigated inside the microfabricated post arrays. A parametric study is conducted to understand how the posts arrangements, distance, and size change the field and field gradients. The results provide criteria where the...
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Spring 2015
Fluorescent proteins (FP) and FP-based biosensors have become essential tools for cell biology and neuroscience research. This thesis describes efforts to engineer new FPs with red emission and novel genetically encoded biosensors based on red FPs. Directed evolution and semi-rational design are...
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Fall 2015
The expansion of the fluorescent protein (FP) colour palette through discovery of more species possessing FPs and by subjecting them to intensive protein engineering efforts has greatly aided the effectiveness of FP-based biosensor designs. Currently, the main FP-based methods for detecting...
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Spring 2013
Research was undertaken into the organic semiconductors tris(8- hydroxyquinoline)aluminum (Alq3) as well as bis(8-hydroxyquinoline)zinc (Znq2) to the effect of improving achievable morphological control using an inexpensive evaporation based solution synthesis method. By varying experimental...
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Integration of Nanomechanical Resonators in Microfluidic Systems for Specific Protein Detection
DownloadFall 2009
Nanomechanical resonators offer a pathway towards highly sensitive and label-free detection of biomolecules by transducing the mass of bound analytes into resonant frequency shifts. Zeptogram level and even single cell detections have been successfully achieved by others. However, these...
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Fall 2016
The field of conducting polymers and mainly organic electrochemical transistors (OECT) have been investigated for bioelectronics applications. Advantages such as conformability, high quality electrical contact, ease of fabrication and biocompatibility made OECTs a great potential of future bio...