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Skip to Search Results- 8Biosensors
- 7Fluorescent proteins
- 5Protein engineering
- 2Diazonium chemistry
- 1Bimolecular fluorescence complementation
- 1Calcium indicator
- 1Abdelfattah, Ahmed
- 1Alford, Spencer Caleb
- 1Assempour, Nazanin
- 1Belal, Ahmed S. F.
- 1Carlson, Haley J
- 1Hoi, Hiofan
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All-Carbon Molecular Electronics: From Flexible Fabrication to Multi-Step Transport and Molecular Optoelectronics
DownloadSpring 2018
The central idea of molecular electronics is to incorporate individual or ensemble molecules into the electronic circuit units in the hope of creating miniaturized functional devices with unique properties. This dissertation aims to present my efforts to pursue this ultimate goal, covering the...
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Carbon-on-Gold Films and Spontaneous Adsorption of Aryldiazonium Salts for Surface Plasmon Resonance Sensing
DownloadFall 2021
Over the past decades, surface plasmon resonance (SPR) technology has gained popularity as a powerful analytical technique for the study of biomolecular interactions and medical diagnostics. This is made possible thanks to the well-established gold-thiolate chemistry. However, the limited...
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Spring 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria jellyfish revolutionized many fields in the scientific community, including molecular biology, protein engineering, and neuroscience. The ability to genetically link a fluorescent protein to a protein of interest has...
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Fall 2016
Fluorescence microscopy is currently the most powerful imaging technique for interrogation of neural circuits. Accordingly, tremendous efforts have been invested in engineering fluorescent proteins (FPs) to act as indicators for various biochemical processes in neural circuits, resulting in a...
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Fall 2012
Fluorescent proteins (FPs) are indispensible biochemical tools. The concerted efforts of protein engineers have produced FPs spanning the visible colour spectrum. This wide variety of FPs has greatly facilitated the development of FP-based biosensors. However, researchers rely on relatively few...
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Spring 2013
Fluorescent protein (FP) technology is now an indispensible tool of biomedical research. Nevertheless, only a few members of the hundreds of existing FPs are generally regarded as the preferred options for most imaging applications. Accordingly, new FPs with ever-improved properties are in demand...
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Fall 2014
The discovery and subsequent applications of fluorescent proteins (FPs) launched a new era for live cell fluorescence imaging. The design and developments of FP-based indicators have further solidified the versatility of FPs and rendered them as indispensable tools in life science research now...
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Spring 2017
Fluorescent proteins (FPs) have dramatically advanced life science research. Since their discovery they have become invaluable tools for imaging living systems and have been developed into precision instruments for measuring normally invisible events such as fluctuations in calcium ion...
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Spring 2015
Fluorescent proteins (FP) and FP-based biosensors have become essential tools for cell biology and neuroscience research. This thesis describes efforts to engineer new FPs with red emission and novel genetically encoded biosensors based on red FPs. Directed evolution and semi-rational design are...