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Fall 2018
Protein kinases are critical players in cell signaling processes and their activity leads to the phosphorylation of substrates, often regulating enzymatic activity. 518 protein kinases are encoded in the human genome, however, there are many features within the catalytic domain of these proteins...
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Fall 2018
Desmosomes are large, complex protein assemblies which, at the most fundamental level, facilitate cellular adhesion. On a grander scale, desmosomes, and more specifically desmosomal networks, are critical for the maintenance of tissue integrity. They link the cytoskeletons of adjacent cells...