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Fall 2015
Vertebrate eye development is a dynamic process that couples morphogenesis, migration of extraocular periocular mesenchyme (POM) cells to the eye, and retinal patterning along the nasotemporal and dorsoventral (DV) axes. Aberrant patterning during ocular development often results in defects...
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Fall 2019
Axial patterning of the developing vertebrate eye is crucial for proper axon pathfinding, as well as critically important morphogenetic events such as closure of the ocular fissure. Perturbations in eye morphogenesis can lead to ocular coloboma (failed ocular fissure closure) and microphthalmia...