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Roles of the Insulin-like Growth Factor-II/Cation-independent Mannose 6-phosphate Receptor and Cathepsin D in Alzheimer’s Disease Pathology
DownloadSpring 2016
Alzheimer’s disease (AD) is the most common type of senile dementia affecting the elderly. A critical contributing factor to the neurodegeneration and development of AD pathology stems from the processing of amyloid precursor protein (APP), leading to the generation of β-amyloid (Aβ) peptides....
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Fall 2012
Autobiographical memories can be recalled through effortful memory search (i.e., generative retrieval). They can also come to mind spontaneously (i.e., direct retrieval). It has long been argued that personal memories are usually generated in word-cueing studies. However, recent research (Uzer,...
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Transition Theory: Evidence from Personal Transitions and Their Role in the Contents and Organization of Autobiographical Memories
DownloadFall 2017
The retrieval curve of autobiographical memories across the lifespan is not an Ebbinghaus forgetting curve; it peaks at adolescence and early adulthood. One mainstream theory of autobiographical memory uses “the self” to explain the reminiscence bump and other phenomena in the field. In this...
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Use of autobiographical memory cues as cognitive support for episodic memory: Comparison of individuals with mild-stage Alzheimer's disease and healthy older adults
DownloadFall 2009
The purpose of the study was to examine the effectiveness of autobiographical memories to support the improvement of episodic memory (i.e., word recall) in patients with mild- stage Alzheimer’s Disease (AD) and healthy older adults. Participants included 20 healthy young-old adults (M Age =...