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Skip to Search Results- 1Abazari Torqabeh, Alireza
- 1Barley, Randall Douglas Corwyn
- 1Bornes, Troy D.
- 1Froentjes, Liesbeth
- 1Godziuk, Kristine D.
- 1Marks, Ray.
- 4Department of Surgery
- 2Department of Physical Therapy
- 1Department of Biomedical Engineering, Department of Electrical and Computer Engineering
- 1Department of Chemical and Materials Engineering
- 1Department of Public Health Sciences
- 1Faculty of Pharmacy and Pharmaceutical Sciences
- 1Adesida, Adetola (Department of Surgery
- 1Adesida, Adetola B. (Surgery)
- 1Bagnall, Keith (Department of Surgery)
- 1Beaulieu, Christian (Biomedical Engineering)
- 1Dr. Keith M. Bagnall, Department of Anatomy, United Arab Emirates University
- 1Dr. Nadr M. Jomha, Department of Surgery, University of Alberta
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Fall 2021
The menisci are a pair of knee joint structures that are wedge-shaped in cross-section and semi-lunar in superior view. They play roles in force distribution that help maintain the health of the articular cartilage. In adults, the menisci can be divided into a fibrous, vascularized outer region...
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Clinical Screening and Identification of Sarcopenic Obesity in Adults with Knee Osteoarthritis
DownloadFall 2019
Background: Obesity [defined using body mass index (BMI)] is associated with knee osteoarthritis (OA) and increased surgical infection risk in total knee arthroplasty (TKA). However sarcopenic obesity, a phenotype of low muscle mass with high fat mass, may have greater relevance and implications...
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Collagen I: an aberrantly expressed molecule in chondrocytes or a key player in tissue stabilization and repair both in vivo and in vitro?
DownloadSpring 2010
Barley, Randall Douglas Corwyn
Extrinsic repair techniques for the treatment of acute chondral injuries continue to yield suboptimal repair. The inability of these techniques to produce hyaline cartilage underscores the limitations in our understanding of basic chondrocyte biology. Conversely, intrinsic repair tissue has not...
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Spring 2014
Physical activity is recommended in the management of arthritis. This thesis utilized the CCHS 2007-2008 to 1) determine what factors modify physical activity in explaining the likelihood of having arthritis; and 2) what demographic, behavioural and medical factors influence physical activity...
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Modeling the transport of cryoprotective agents in articular cartilage for cryopreservation
DownloadSpring 2011
Loading vitrifiable concentrations of cryoprotective agents is an important step for cryopreservation of biological tissues by vitrification for research and transplantation purposes. This may be done by immersing the tissue in a cryoprotective agent (CPA) solution, and increasing the...
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Fall 2014
Osteoarthritis (OA) is characterized by progressive destruction of articular cartilage, subchondral bone sclerosis, and osteophyte formation. Currently there is no disease modifying drug for treatment of OA. Usually OA is not diagnosed until the advanced stages, where palliative treatment is the...
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Fall 2010
Osteoarthritis is characterized by pain and inflammation in joints, typically weight-bearing joints such as the knee. An early warning sign of osteoarthritis is the loss of proteoglycan molecules in the cartilage matrix. A surrogate method for measuring proteoglycan loss is detection of sodium...
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Fall 2016
Articular cartilage injury is a major risk factor for the development of osteoarthritis, a condition that results in significant patient morbidity and substantial cost to the healthcare system. Due to the limited capacity of articular cartilage to regenerate, early intervention is required to...