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Functional characterization of class I Arfs and their Guanine Nucleotide Exchange Factors at the Golgi complex
DownloadFall 2009
We examined the function of ADP-ribosylation factors (Arfs) and their guanine nucleotide exchange factors (GEFs) that regulate recruitment of coat proteins on the Golgi complex. The large ArfGEF GBF1 localizes at the cis-Golgi complex while BIG1 and BIG2 localize at the trans-Golgi network...
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Regulation of HCV Cell-to-Cell Spread by ADP-ribosylation factor 1-Dependent Regulation of Cytosolic Lipid Droplet Homeostasis
DownloadSpring 2018
Hepatitis C virus (HCV) infects cells via cell-free virions by direct cell-to-cell transmission. Entry of cell-free HCV virions has been fairly well-characterized. Several host factors involved in this process have been identified, including the cell surface receptors, tight junction molecules,...