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Skip to Search Results- 15Graduate and Postdoctoral Studies (GPS), Faculty of
- 15Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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A randomized control trial of azithromycin for the acute management of wheezy pre-school children
DownloadFall 2017
Silbernagel, Patricia del Rocio
Objective: We sought to determine if azithromycin, a macrolide antibiotic with anti-inflammatory(1,2), antibacterial(3) and potential antiviral(4) properties, added to routine therapy of wheezy pre-school children would resolve respiratory symptoms more rapidly, and protect against symptom...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Bacillus thuringiensis isolates from the Philippines: habitat distribution, delta-endotoxin diversity, and toxicity to rice stem borers (Lepidoptera: Pyralidae)
Download1998
Cohen, M. B., Aguda, R. M., Bottrell, D. G., Gould, F. L., Litsinger, J. A., Theunis, W., Peferoen, M., Cruz, W. T., Decock, C., Lambert, B.
Abstract: Bacillus thuringiensis Berliner isolates were detected in 57% of 801 samples of rice grain dust, soil, rice field arthropods, and miscellaneous habitats (rice straw compost and mammal faeces) collected at 100 sites in the Philippines. The collection yielded 3950 isolates of B....
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Spring 2019
Background: Children are at high risk for malnutrition during hospital admission. Over half of children admitted to hospital will exhibit signs of nutrition deterioration such as weight loss. Screening for malnutrition is a critical step in the nutrition care process, however there is currently a...
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Fall 2023
Proliferating cells, such as neonatal cardiomyocytes, have a high Warburg effect, which is a metabolic state in which there is high rates of glycolysis uncoupled from glucose oxidation under aerobic conditions. The Warburg effect is typically seen in cancerous cells and actively proliferating...
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Fall 2021
Background: Celiac disease (CD) is an autoimmune disease that results in inflammation and damage to the small intestine when gluten, a protein found in wheat, rye or barley is consumed. The only treatment for CD is lifelong adherence to the gluten-free diet (GFD). However, dietary intake can be...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...