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Skip to Search Results- 1Eugenio, Luiz
- 1Hussack, Greg
- 1Kitova, Elena N.
- 1Klassen, John S.
- 1Murase, Tomohiko
- 1Ng, Kenneth K. S.
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Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile
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Ng, Kenneth K. S., Tanha, Jamshid, Kitova, Elena N., Eugenio, Luiz, Murase, Tomohiko, Klassen, John S., Hussack, Greg, Schorr, Melissa
Clostridium difficile infection is a serious and highly prevalent nosocomial disease in which the two large, Rho-glucosylating toxins TcdA and TcdB are the main virulence factors. We report for the first time crystal structures revealing how neutralizing and non-neutralizing single-domain...