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- 2Anti-cancer
- 1Breast cancer
- 1Cell membrane
- 1Conjugated linoleic acid
- 1D112
- 1Delocalized lipophilic cation
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Deciphering the mechanism of cytotoxicity and cancer-selective activity of the delocalized lipophilic cation D112
DownloadFall 2016
Chemotherapeutic drugs that are used in anti-cancer treatments often cause death of both cancerous and noncancerous cells. This non-selective toxicity is the root cause of untoward side effects that limits the effectiveness of therapy. To improve the therapeutic options for cancer patients, there...
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Establishing the anti-cancer effects of unsaturated fatty acids and a novel oil on human breast cancer cells
DownloadFall 2012
N-3 and n-6 fatty acids and conjugated linoleic (CLA) acid have been known to inhibit breast cancer cell growth, however, effects on normal cells and of single and mixtures of n-3 and n-6 pathway intermediates have not been thoroughly investigated. The objective of this thesis was to determine...
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