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Skip to Search Results- 6Analgesia
- 2Experimental Autoimmune Encephalomyelitis
- 2Multiple sclerosis
- 2Pain
- 1Analgesics--Administration
- 1Anesthesia
- 1Catuneanu, Ana
- 1Chadwick, Caylin Isabelle
- 1Dorfman, Tamara L.
- 1Duggleby, Wendy Diane.
- 1Dworsky-Fried, Zoë
- 1Walker, Nancy Carol.
- 1Clayton T. Dickson (Psychology, Physiology, Anesthesia and Pain Medicine, Neuroscience and Mental Health Institute)
- 1Kerr, Bradley (Anesthesiology & Pain Medicine)
- 1Kerr, Bradley (Anesthesiology and Pain Medicine)
- 1Kerr, Bradley (Neuroscience and Mental Health Institute, Anesthesiology and Pain Medicine, Pharmacology)
- 1Rempel, Gwen (Faculty of Nursing)
- 1Taylor, Anna (Pharmacology)
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Chronic Pain in a Mouse Model of Multiple Sclerosis: Contributions of the Kappa Opioid System
DownloadFall 2021
The perception of pain is a multimodal experience that is encoded by regions of the central nervous system (CNS) that are involved in sensation, affect, and cognition. Chronic pain is not merely the persistence of pain, but a debilitating condition that is associated with neurochemical...
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Instruments for Scoring Pain, Non-Pain Related Distress, Analgesia, and Sedation in Pediatric Mechanically Ventilated Patients and their Efficacy and Effectiveness in Practice: A Systematic Review
DownloadFall 2012
Objective pain and sedation assessment scales to standardize measures of distress in mechanically ventilated pediatric patients are increasingly available, but few have been evaluated for efficacy and effectiveness in this population. The purpose of paper one was to identify and evaluate...
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Pain and analgesia in experimental autoimmune encephalomyelitis: Contribution of the central nucleus of the amygdala
DownloadSpring 2021
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation, degeneration and demyelinating lesions within the central nervous system. Chronic pain is a highly prevalent symptom associated with MS, affecting 50-80% of patients over the course of their disease....
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Sex Differences in Central Nervous System Plasticity and Pain in Experimental Autoimmune Encephalomyelitis
DownloadSpring 2019
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease with many known structural and functional changes in the central nervous system (CNS). A well-recognized, but poorly understood, complication of MS is chronic pain. Little is known regarding the influence of sex on the development...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...