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- 15Randomized Controlled Trials as Topic
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- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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Developing a Patient-Driven Arts-Based Knowledge Translation Tool for Parents of Children with Asthma
DownloadSpring 2016
Background: Family-centered education is critical to managing childhood asthma, the most common chronic disease of childhood in North America. Parents are largely responsible for the day-to-day management of their child’s asthma; as such, finding effective ways to educate parents about asthma is...
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Development of a Targeted Adenoviral Vector Expressing HSV-TK for use in Breast Cancer Gene Therapy and Analysis through Positron Emission Tomography
DownloadFall 2012
While adenoviral (Ad) vectors are the most commonly used gene delivery vector for human gene therapy, improvements must be made to increase Ad specificity to tumors if they are to be used for cancer gene therapy. Our goal is to target adenoviral vectors to breast cancer (BrCa) cells to induce...
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Spring 2012
Asthma is a common chronic condition in Canadian adolescents. Stress is a proposed risk factor for asthma development. Allostatic load (AL) is a composite measure of chronic stress exposure, and its role in the development of asthma in adolescents was the focus of this thesis. In study 1, we...
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Effect of Adenovirus-mediated Decorin Gene Therapy on Fibrotic Remodeling in Tissue-engineered Skin
DownloadFall 2016
Background: Hypertrophic scar (HTS) is a fibroproliferative disorder of the skin that results in the development of painful, red, raised scar lesions. Transforming growth factor beta 1 (TGF-β1) has been implicated as a key driver of this disorder. Primarily, these effects include an increased...
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Engaging First Nation and Inuit communities in asthma management and control: Assessing cultural appropriateness of educational resources.
Download2013
Chera, R., Fenton, N., E., Elliott, S., Latycheva, O., Stewart, M., Hampson, C., Masuda, J., R.
Introduction: Asthma is a growing concern in First Nations and Inuit communities. As with many health indicators and outcomes, Aboriginal peoples living in remote areas experience greater disparities in respiratory health compared with non-Aboriginal Canadians. Therefore, it is critically...