Search
Skip to Search Results- 42Asthma
- 15Randomized Controlled Trials as Topic
- 10Acute Disease
- 8Anti-Asthmatic Agents
- 7Adenovirus
- 6Gene therapy
- 29Graduate and Postdoctoral Studies (GPS), Faculty of
- 29Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 16Emergency Medicine, Department of
- 16Emergency Medicine, Department of/Reviews (Emergency Medicine)
- 5Nursing, Faculty of
- 5School of Public Health
-
Fall 2009
International prevalence of ever asthma and current wheeze in adults were examined in 55 countries participating in the World Health Survey. The prevalence of ever asthma ranged from 1.1-7.9% in Asia, 2.4-7.6% in Africa, 3.4-7.9% in Middle East, 2.4-12.1% in America, 3.9-6.8% in Eastern Europe,...
-
Mapping intracellular cytokine pools in granulocytes: Dynamic storage and trafficking sites of interleukin-9 and interleukin-13 in human eosinophils
DownloadFall 2020
Eosinophils are immune cells with constantly evolving roles in both innate and adaptive immunity and have long been associated with the predominant pathology of the human airways, asthma. Eosinophils are specialized in their granulocytic nature, possessing several membrane-bound secretory...
-
Maternal Depressive Symptoms across Early Childhood and Asthma in School Children: Findings from a Longitudinal Australian Population Based Study
Download2015
Cooklin, Amanda, Kozyrskyj, Anita, Bahreinian, Salma, Brown, Stephanie, Kingston, Dawn, Giallo, Rebecca
There is a growing body of evidence attesting to links between early life exposure to stress and childhood asthma. However, available evidence is largely based on small, genetically high risk samples. The aim of this study was to explore the associations between the course of maternal depressive...
-
Mechanistic studies on the uptake and intracellular trafficking of DNA complexes in primary cells using lipid-modified cationic polymers as non-viral gene carrier
DownloadFall 2012
This thesis work is aimed at addressing some of the fundamental questions surrounding the intracellular fate of plasmid DNA in clinically-relevant primary cells, when delivered with lipid-modi!ed cationic polymers as gene carriers. We developed an optimized procedure for the transfection of...
-
Ocular Gene Transfer in the Spotlight: Implications of Newspaper Content for Clinical Communications
Download2014-10-24
Bubela, Tania, Benjaminy, Shelly
Background Ocular gene transfer clinical trials are raising hopes for blindness treatments and attracting media attention. News media provide an accessible health information source for patients and the public, but are often criticized for overemphasizing benefits and underplaying risks of novel...
-
Outdoor Air Pollution and Children´s Asthma in the Census Metropolitan Area of Edmonton, Alberta: the Influence of Place of Residence and Socioeconomic Position
DownloadFall 2016
Background: Asthma is the most common chronic respiratory disease in children and air pollution has been implicated in its development and exacerbations worldwide. The Census Metropolitan Area of Edmonton (CMAE), Alberta, has unique air pollution sources (traffic and industrial related air...
-
Fall 2013
Physician training influences the care that a patient receives. A retrospective cohort of children over 6 years of age, seen in a multi-disciplinary asthma clinic between 2009 and 2010 and followed to 2012, was completed to identify differences in pediatric asthma management by physician...