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Skip to Search Results- 1Abiodun Bello
- 1Bak, Jessi J.
- 1Beggs, Megan R
- 1Bhullar, Harneet
- 1Chow, Patrick Y. T.
- 1Desai, Prajakta V
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Antagonistic modulation of spontaneous neural network activities in isolated newborn rat brainstem preparations by opioids and methylxanthines
DownloadFall 2012
Apnea of prematurity is a common problem among the infants born before term pregnancy. Administration of respiratory stimulating drugs methylxanthines is the most frequent therapy, often in combination with the use of intubation. Opioids are used to reduce the pain associated with intubation,...
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Fall 2012
ATP actions on central inspiratory networks are determined by a three-part signaling system comprising: i) excitatory actions of ATP at P2 receptors (Rs) ii) ectonucleotidases that degrade ATP into adenosine (ADO), and iii) inhibitory actions of ADO at P1Rs. During hypoxia, an initial increase in...
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Calcium and Vitamin D Intake During Pregnancy and Postpartum in the Alberta Pregnancy Outcomes and Nutrition (APrON) Study
DownloadFall 2016
Calcium and vitamin D are important in maintaining a healthy pregnancy. Low intake/status has been associated with preeclampsia, preterm delivery, lower birth weight, poor fetal skeletal growth, reduced bone mass, and excessive maternal bone loss. Rarely have these nutrients been examined...
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Spring 2012
Myocardial energy substrate metabolism is subjected to significant changes during ischemia and reperfusion (I/R), which can greatly influence post-ischemic recovery of left-ventricular (LV) mechanical function. One of the main mechanisms that contribute to I/R injury is the accumulation of...
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Spring 2021
Hyperphosphatemia, elevated serum phosphate (Pi), is an electrolyte imbalance frequently associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD). There are many negative consequences of hyperphosphatemia including worsening renal function, secondary hyperparathyroidism,...
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Fall 2023
Central to calcium homeostasis and bone health is adequate intestinal calcium absorption. Calcium from the diet is absorbed via either a transcellular or a paracellular pathway both of which are regulated by calciotropic hormones. In cases of low dietary calcium availability, a transcellular...
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Fall 2012
Kidney stones and osteoporosis are prevalent clinical conditions posing a large economic burden to the healthcare system. A common risk factor for both these diseases is hypercalciuria, which is the inappropriate excretion of calcium in urine. Changes in serum calcium levels are detected by the...