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Skip to Search Results- 1Abu-Sa'da, Omar SD
- 1Ahrari, Malema
- 1Alles, Sascha R
- 1Chen, Yishen
- 1Cordingley, Dean M.
- 1Dimopoulos, Ioannis
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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Spring 2021
As one of the most accessible primary health care providers, pharmacists are in an excellent position to provide primary health care services. Although slow, the current transition from a dispensing-centered (transaction-based) pharmacy approach to a patient-centered (patient care based) approach...
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The Effect of Caffeine on the Neurobehavioral and Neuropathological Outcome of the Newborn Rat
DownloadSpring 2010
Caffeine is used for the treatment of apnea of prematurity. The objective of this study was to determine the long term neuropathological and neurobehavioral effects of caffeine on the immature rat brain. Newborn rats were injected with either caffeine, or normal saline from postnatal days 3 to 7,...
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The Neonatal Locus Coeruleus is a Differentiated and Complex Neuromodulatory System as Revealed by Local Field Potential Analysis
DownloadSpring 2019
The locus coeruleus (LC) in the pons of the brainstem provides the sole source of noradrenergic afferent input to most brain structures including the cerebral cortex, hippocampus, cerebellum and spinal cord. The resulting modulation of activity is important for controlling behaviors like...
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Fall 2015
Nucleosides are essential for RNA and DNA synthesis. They also play a central role in other cellular metabolic pathways, and modulate a diverse array of physiological processes, including renal and cardiovascular function and neurotransmission. Due to their hydrophilic nature, specialized...
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The effect of long-term interleukin-1 beta exposure on sensory neuron electrical membrane properties: implications for neuropathic pain
DownloadSpring 2011
The effect of interleukin-1 beta (IL-1β) on the electrical properties of sensory neurons was assessed at comparable levels and exposure times to those found in animal models of neuropathic pain. Experiments involved whole cell current- or voltage-clamp recordings from rat dorsal root ganglion...