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Delineating the biology of Anaplastic Lymphoma Kinase (ALK) and its resistance to crizotinib
DownloadFall 2017
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase receptor that was initially identified as a potent oncogenic driver in anaplastic large-cell lymphoma (ALCL) in the form of NPM-ALK fusion protein. Various forms of oncogenic ALK proteins have been identified, subsequently, in various...
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