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- 11 Introduction
- 12 Supra-physiological Insulin Levels Elevate Palmitate Oxidation to Improve Neonatal Rabbit Heart Ischemia-Reperfusion Recovery
- 13 Neonatal Rabbit Aorto-Caval Shunt Volume-Overload Cardiac Hypertrophy Model
- 14 Cardiac Hypertrophy in the Newborn Delays the Maturation of Fatty Acid β-Oxidation and Compromises Post-ischemic Functional Recovery
- 15 Activating Peroxisome Proliferator-Activated Receptor Prevents Post-Ischemic Contractile Dysfunction in the Hypertrophied Neonatal Heart
- 16 General discussion
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Spring 2012
The surgical repair of congenital heart defects (CHDs) often requires a bloodless/motionless field achieved by arresting the neonatal heart and exposing it to a period of ischemia. Metabolic manipulation, such as suppression of fatty acid (FA) oxidation, improves post-ischemic functional recovery...
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