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1Wong, Jordan M.

Subject / Keyword

1Biomaterial
1Islet Transplantation
1Localized Immunomodulation
1Microparticles
1Rapamycin
1Type 1 Diabetes

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1Graduate and Postdoctoral Studies (GPS), Faculty of
1Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations

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1English

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1Thesis

Departments

1Department of Surgery

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1Pepper, Andrew (Surgery)

Exploring New Avenues in Islet Transplantation: Localized Immune Modulations with Rapamycin-Eluting Microparticles
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Fall 2024

Wong, Jordan M.

Islet transplantation (ITx) is an effective means to restore physiologic glycemic regulation in those living with type 1 diabetes; however, lifelong systemic immunosuppression required to subvert the immune response remains a major barrier to patient inclusion. While these drug therapies delay...

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Exploring New Avenues in Islet Transplantation: Localized Immune Modulations with Rapamycin-Eluting Microparticles