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Effects of dietary and pharmacological interventions on pancreatic β-cell compensation in Nile rats: a model for spontaneous type 2 diabetes
DownloadFall 2019
Insulin-secreting pancreatic β-cells adapt to obesity-related insulin resistance via increases in insulin secretion and β-cell mass, which is referred to as β-cell compensation. Failed β-cell compensation predicts the onset of type 2 diabetes (T2D). However, the mechanisms underlying β-cell...
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