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Biosynthetic Studies of Resorcylic Acid Lactones, Hypothemycin, Radicicol, and Dehydrocurvularin
DownloadFall 2013
Fungal polyketides, a vast source for pharmaceutical industries, are biosynthesized by multifunctional iterative polyketide synthases (PKS). The biosynthesis employs complex programming rules, which are currently unresolved. To decode the programming rules, the biosynthesis of three polyketides,...
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