Search
Skip to Search Results- 11Systematic reviews
- 4Child health
- 3Knowledge translation
- 2Drug therapy
- 2Randomized controlled trials
- 2Research use
-
2012
Thomson, D., Chisholm, A., Hartling, L., Dryden, D. M.
Background: Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. Objectives: To describe the methodological approaches in overviews of interventions. Design: Descriptive study. Methods: We searched 4 databases from 2000 to...
-
2006
Estabrooks, C.A., Hofmeyer, A., Thompson, D.S., Lovely, J.J.E.
Despite calls over several decades for theory development, there remains no overarching knowledge-translation theory. However, a range of models and theoretical perspectives focused on narrower and related areas have been available for some time. We provide an overview of selected perspectives...
-
2014
Hamm, M. P., Shulhan, J., Milne, A., Williams, G., Scott, S. D., Hartling, L.
Background: Social media use is highly prevalent among children, youth, and their caregivers, and its use in healthcare is being explored. The objective of this study was to conduct a systematic review to determine: 1) for what purposes social media is being used in child health and its...
-
Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthma.
Download2011
Seida, J., Vandermeer, B., Hartling, L., Dryden, D. M., Rowe, B. H., Bond, K.
Background The Risk of Bias (RoB) tool is used to assess internal validity of randomized controlled trials (RCTs). Our objectives were to: 1) evaluate inter-rater agreement of the RoB tool; 2) determine the time to access supplemental study information; 3) compare the RoB tool with the Jadad...
-
Children are not just small adults: the urgent need for high-quality trial evidence in children.
Download2008
Offringa, M., Hartling, L., Craig, J. C., Klassen, T. P.
Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...
-
Controlled trials in children: quantity, methodological quality and descriptive characteristics of pediatric controlled trials published 1948-2006.
Download2010
Tjosvold, L., Thomson, D., Vandermeer, B., Klassen, T. P., Cohen, E., Hartling, L.
Background The objective of this study was to describe randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in child health published between 1948 and 2006, in terms of quantity, methodological quality, and publication and trial characteristics. We used the Trials Register...
-
From the trenches: a cross-sectional study applying the GRADE tool in systematic reviews of healthcare interventions.
Download2012
Dryden, D. M., Vandermeer, B., Seida, J., Hartling, L., Fernandes, R. M.
Background GRADE was developed to address shortcomings of tools to rate the quality of a body of evidence. While much has been published about GRADE, there are few empirical and systematic evaluations. Objective To assess GRADE for systematic reviews (SRs) in terms of inter-rater agreement and...
-
Protocol for a systematic review of the use of narrative storytelling and visual-arts-based approaches as knowledge translation tools in healthcare.
Download2013
Scott, S. D., Brett-Maclean, P., Archibald, M., Hartling, L.
Background The arts are powerful, accessible forms of communication that have the potential to impart knowledge by attracting interest and developing meaningful connections. Knowledge translation aims to reduce the ‘evidence-practice’ gap by developing, implementing and evaluating strategies...
-
Quantifying bias in randomized controlled trials in child health: a meta-epidemiological study.
Download2014
Hartling, L., Vandermeer, B., Dryden, D. M., Fernandes, R. M., Hamm, M. P.
Objective: To quantify bias related to specific methodological characteristics in child-relevant randomized controlled trials (RCTs). Design: Meta-epidemiological study. Data Sources: We identified systematic reviews containing a meta-analysis with 10–40 RCTs that were relevant to child health in...
-
Steroids and bronchodilators for acute bronchiolitis in the first two years of life: systematic review and meta-analysis.
Download2011
Bialy, L., Klassen, T. P., Hartling, L., Vandermeer, B., Johnson, D., Milne, A., Plint, A., Fernandes, R. M.
Objective To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years. Design Systematic review and meta-analysis. Data sources Medline, Embase, Central, Scopus, PubMed, LILACS,...