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Skip to Search Results- 13Glover, Mark (Biochemistry)
- 1Bhavsar, Amit (Medicine & Dentistry)
- 1Hendzel, Michael (Oncology)
- 1Holmes, Charles (Biochemistry)
- 1Ismail, Ismail (Oncology)
- 1Raivio, Tracy (Biological Sciences)
- 1Burkat, Michael
- 1Campbell, Stephen J.
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Site-directed mutagenesis of charged amino acid residues on the CpxASD and CpxP in E. coli, potentially important for signaling and direct interaction
DownloadSpring 2019
Bacterial pathogens must endure diverse environmental stresses that they encounter while colonizing and infecting a host. Two-component signal transduction systems (TCSTs) are the most widespread regulatory systems in bacteria, but importantly absent in mammals. In general, TCSTs sense and...
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Structural insight of transcriptional terminator recognition by ProQ/FinO domain RNA chaperones
DownloadFall 2022
The ProQ/FinO family is an emerging group of RNA binding proteins that are critical for sRNA-mediated gene regulation in proteobacteria. The ProQ/FinO domain of these proteins recognizes a transcriptional terminator, hairpin-tail structure, to regulate gene expression. The important role of the...
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Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...