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Molecular regulation and endogenous expression of CRTh2 in in vitro differentiated CRTh2+ Th2 cells
DownloadFall 2011
Allergic inflammation is mediated by T helper 2 (Th2) cells. Chemoattractant receptor homologous molecule expressed on Th2 cells (CRTh2) is expressed by Th2 cells and mediates chemotaxis and production of the Th2 cytokines interleukin (IL)-4, IL-5 and IL-13. To understand the molecular...
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Spring 2014
CRTh2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) is a marker for Th2 cells and activation through CRTh2 stimulates expression of cytokines that are important for allergic responses such as IL-4, IL-5 and IL-13. We have observed CRTh2+ T cells express the IL-25 receptor...