Search
Skip to Search Results- 366Faculty of Pharmacy and Pharmaceutical Sciences
- 4Faculty of Medicine
- 2Faculty of Medicine and Oral Health Sciences
- 1Department of Biomedical Engineering
- 1Department of Medical Sciences
- 1Department of Medicine
- 1AL Omair, Omar Abdulrahman
- 1AL-AGILI, MARWA
- 1Abdelmoneim, AS
- 1Abdulsalam Alharbi
- 1Abdussalam, Ali MA
- 1Abed,Hadeel
- 15Pharmacokinetics
- 8Cytochrome P450
- 6Cancer
- 6Monoclonal antibodies
- 6Polymeric micelles
- 5Arachidonic acid
- 8El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 5Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
- 5Yuksel, Nese (Faculty of Pharmacy and Pharmaceutical Sciences)
- 4Doschak, Michael (Pharmacy and Pharmaceutical Sciences)
-
Fall 2017
Abstract Rheumatoid arthritis (RA) is a chronic, progressive, and systemic inflammatory condition leading to joint destruction, substantial pain, and functional disability. Patients with RA have a higher morbidity and mortality rate because of cardiovascular (CV) complications than the general...
-
Downregulation of the FOXM1 transcription factor by dual nitric oxide-/ hydrogen sulfide-donors: preliminary structure-activity relationships
DownloadFall 2015
Rodriguez Dimitrescu, Alexandra
In recent decades, the Forkhead Box (FOX) family of transcription factors (e.g. FOXM1) has attracted the attention of the scientific community due to its significant role in cancer initiation and progression. Furthermore, the abnormal or deregulated expression of FOXM1 has been associated with...
-
Fall 2009
Osteoporosis is a skeletal disorder that affects millions of people worldwide, and is characterized by the accelerated loss of bone mass. Current anti-resorptive drug approaches such as bisphosphonates and salmon calcitonin exhibit severe side effects and very low bioavailability, respectively....
-
Fall 2012
Cardiometabolic syndrome refers to a clustering of several risk factors for cardiovascular disease; obesity and hyperlipidemia are two underlying disorders associated with the syndrome. An often overlooked aspect of these conditions is the effect that they may have on the pharmacokinetics of...
-
Spring 2011
Previous studies have shown growth hormone and therapeutic low intensity pulsed ultrasound can enhance mandibular growth separately. The aim of this study is to evaluate the concomitant effect of both of these applications on mandibular growth in rat. Methods: 24 male Sprague Dawley rats were...
-
Fall 2017
The pharmacokinetics of dronedarone, effect of hyperlipidemia on dronedarone disposition and dronedarone tissue distribution in normolipidemic (NL) and hyperlipidemic (HL) rats were studied. Novel and sensitive HPLC-UV and LC-MS reverse phase assay methods were developed. Rat plasma (100 μL) was...
-
Effects of alendronate and vitamin D on metabolomic profiles in a rat model of osteoporosis
DownloadSpring 2019
Osteoporosis is a progressive bone disease and a significant global medical issue, which places a serious economic and health burden on individuals, families and societies. It is well known that early diagnosis of osteoporosis has a vital role in reducing the burden and complications of excessive...