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- 1AL Omair, Omar Abdulrahman
- 1AL-AGILI, MARWA
- 1Abdelmoneim, AS
- 1Abdulsalam Alharbi
- 1Abdussalam, Ali MA
- 7Cytochrome P450
- 6Monoclonal antibodies
- 5Epoxyeicosatrienoic acids
- 5Polymeric micelles
- 7El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 5Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
- 4Doschak, Michael (Pharmacy and Pharmaceutical Sciences)
- 4Jamali, Fakhreddin (Pharmaceutical Sciences)
- 3El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
Ischemic heart disease (IHD) is a significant cause of morbidity and mortality for Canadians. While mortality rates from myocardial infarction (MI) and heart failure (HF) have decreased, IHD remains the number one cause of premature mortality. Both age and sex are important contributors for IHD...
COPD case-finding and management in community pharmacy: informing pharmacists to improve patient careDownload
Pharmacists could have an important role to play in reducing the increasing societal burden of Chronic Obstructive Pulmonary Disease through the professional services they provide. The overall objective of this thesis is to contribute to a multi-phased research aimed at developing an intervention...
Development and partial validation of a bioanalytical assay for the detection of a novel bone-targeting parathyroid hormone conjugate using metal-free LC-MS/MSDownload
In an effort to address shortcomings with current drug treatments for osteoporosis (OP) and improve the efficacy of human parathyroid hormone (hPTH(1-34)), we have employed a bisphosphonate-conjugation strategy by tethering hPTH(1-34) to a non-nitrogenated bisphosphonate (BP) moiety (BP-PTH) in...
Medication appropriateness is a fundamental target for the healthcare system, particularly in relation to older adults. Because polypharmacy and multimorbidity are prevalent in older adults, they are more prone to the risks of having an inappropriate medication. They are also more prone to...
In 2007, Additional Prescribing Authorization (APA) was introduced in Alberta, which allows pharmacists to independently initiate prescriptions and prescribe to manage ongoing therapy. Pharmacist prescribing has also been shown to have positive patient outcomes in a variety of health conditions....
Development of active tumor targeting systems for delivery of siRNA and drugs into breast and colorectal cancerDownload
Active targeting strategies have been pursued to improve the efficacy and safety of cancer therapeutics and theranostics. The significant benefit of tumor homing ligands conjugated to small molecules versus nanoparticle delivery systems in enhancing drug delivery to the tumor is still a matter of...
Breast cancer is the second most common cancer in women, and the leading cause of cancer-related deaths among women. Conventional breast cancer therapeutic strategies such as surgical removal of tumor, radiation therapy and chemotherapy have several limitations and non-specific effects on...
Electronic Medication Administration Records and Barcode Medication Administration to Support Safe Medication Practices in Long-term Care FacilitiesDownload
Abstract Medication incidents are common in long-term care facilities (LTCF). While few contribute to permanent disability or death, a significant proportion lead to resident harm. Technology solutions have been proposed to improve medication safety in long-term care environments, with...
Type 2 diabetes (T2D) is associated with an increased risk for cardiovascular disease. Of interest, liraglutide, a therapy for T2D that activates the glucagon-like peptide-1 receptor (GLP-1R) to augment insulin secretion, reduces cardiovascular-related death in people with T2D. However, it...