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Skip to Search Results- 364Faculty of Pharmacy and Pharmaceutical Sciences
- 117Department of Biomedical Engineering
- 11Department of Medical Sciences
- 6Department of Electrical and Computer Engineering
- 5Department of Mechanical Engineering
- 4Faculty of Medicine
- 1AL Omair, Omar Abdulrahman
- 1AL-AGILI, MARWA
- 1Abbasi Dezfouli, Meysam
- 1Abdelmoneim, AS
- 1Abdulsalam Alharbi
- 1Abdussalam, Ali MA
- 15Pharmacokinetics
- 12MRI
- 8Cytochrome P450
- 7Cancer
- 6Magnetic Resonance Imaging
- 6Monoclonal antibodies
- 9Wilman, Alan (Biomedical Engineering)
- 8Beaulieu, Christian (Biomedical Engineering)
- 8El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 5Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
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Repositioning study of flubendazole for treating lung cancer and meningoencephalitis using an oral lipid nanosystem
DownloadFall 2023
Nanoemulsions have wide application, presenting several properties such as the solubilization of poorly soluble drugs in water, promoting the increase of their bioavailability, allowing greater stability of the formulation and, due to its property as a carrier, promoting their modified release....
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Exploring Women’s Experiences with Deciding to Use and Access Long-Acting Reversible Contraception
DownloadFall 2023
Women spend nearly half their life able to become pregnant. Despite the growing number of contraceptive options available, women continue to select user-dependent options over the user-independent long-acting reversible contraception (LARC). This in part contributes to the current rate of...
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Spring 2023
As the most metabolically demanding organ in the body, the heart must continually produce extraordinary amounts of energy to sustain constant contractile function. To accommodate for alterations in fuel source availability, the healthy mature heart is omnivorous and possesses the capacity to...
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Fall 2023
The human hippocampus is difficult to image given its small size, location, shape, and complex internal architecture. Structural magnetic resonance imaging (MRI) has shown that typical age-related hippocampal volume changes vary along its anterior–posterior axis. Diffusion tensor imaging (DTI)...
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Laying the foundation for a community pharmacist intervention to improve pneumococcal vaccine uptake
DownloadSpring 2023
Background: Pneumonia is an invasive infectious disease of the lower respiratory tract that reduces the lungs’ ability to transport oxygen in an individual and can be fatal. Among the various pathogens, Streptococcus pneumoniae is a common bacterial cause of community-acquired pneumonia....
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Quantitative Susceptibility Mapping in Human Brain: Short Echo Timing, Thin Slab, and Non-harmonized Multisite Applications
DownloadSpring 2023
Quantifying tissue magnetic susceptibility provides a non-invasive way to monitor iron and myelin abnormalities associated with several neurodegenerative diseases. Quantitative susceptibility mapping (QSM) is a post-processing technique that retrieves the susceptibility distribution from the...
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Development of A Gadolinium-Based Nanotheranostics Platform for Irradiation Activatable MRI-Radiosensitization and Doxorubicin Release in Cancer Therapy
DownloadSpring 2022
The ultimate goal of this thesis research was to design, fabricate, and characterize an integrated nanotheranostics platform for activatable doxorubicin delivery and simultaneous MRI- radiosensitization for synergistic cancer therapy, targeting breast cancer treatment. As shown in the diagram,...
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Spring 2022
Targeting DNA repair enzymes has attracted much attention in recent years to overcome the therapeutic resistance in cancer therapy. Inhibition of DNA repair enzymes can be used to make cancer cells sensitive to the DNA damaging effect of ionizing radiation or chemotherapy. In addition, the...
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The Cardioprotective Role of the N-3 PUFA Metabolite 19,20-Epoxydocosapentaenoic Acid (19,20-EDP) in the Setting of Ischemia Reperfusion Injury
DownloadSpring 2022
Ischemic heart disease (IHD) is a leading cause of cardiovascular morbidity and mortality worldwide. Myocardial ischemia occurs when a coronary artery is occluded and consequently blood supply to the heart is restricted depleting it of oxygen and nutrients. Although early myocardial reperfusion,...