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Skip to Search Results- 2Muller, Milan J.
- 1Abeywardena, Mahinda Yapa
- 1Abou-Chehade, Kassim D.
- 1Adjei, Alex Asiedu.
- 1Al-Majed, Abdulhakeem A
- 1Ali, Mohammad M. A.
- 5Rats as laboratory animals.
- 4GABA. Receptors.
- 4Metalloproteinases. Physiological effect.
- 4Pharmacology
- 3Adenosine
- 3Autophagy
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Small-molecule inhibitors of non-structural protein 15 (NSP15) for the treatment of SARS-CoV-2
DownloadFall 2022
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic. As of 2022, the viral spread is still ongoing and has claimed the lives of at least 6.24 million globally. Despite being more than two years into the...
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Fall 2017
Protein prenylation is the post-translational addition of isoprenoid lipid moieties to proteins, which regulates their subcellular localization and function. Farnesyl or geranylgeranyl isoprenoids are covalently linked to cysteines residues in a C-terminal prenylation recognition sequence in...
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...
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Spring 2021
As one of the most accessible primary health care providers, pharmacists are in an excellent position to provide primary health care services. Although slow, the current transition from a dispensing-centered (transaction-based) pharmacy approach to a patient-centered (patient care based) approach...