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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Logus, J. Wayne (John Wayne), 1951-
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 8Primary Biliary Cholangitis
- 7Inflammatory bowel disease
- 6Inflammatory Bowel Disease
- 5Acute myeloid leukemia
- 5Endothelial cells
- 4B cells
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In silico analysis of changes in predicted metabolic capabilities of intestinal microbiota after fecal microbial transplantation for treatment of recurrent Clostridioides difficile infection
DownloadSpring 2023
Importance: Fecal microbial transplantation (FMT) is effective in treating recurrent Clostridioides difficile (RCDI) infection. The therapeutic efficacy of FMT is thought to be related to restoration of intestinal microbial composition and diversity and key microbially derived compounds, such as...
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A Review of the Appropriate Usage and Efficacy of Iron Replacement Therapy in Gastroenterology Inpatients: Is Intravenous Iron Overutilized?
DownloadSpring 2023
Background: Iron deficiency anemia (IDA) is highly prevalent in patients with gastrointestinal disease. Therefore, appropriate replacement therapy is an essential component of management. Both intravenous (IV) and oral (PO) iron replacement therapies (IRT) are effective. There are concerns,...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Functional Assessment on the Differential Effect of Mutant p53-Plakoglobin Interaction in Carcinoma Cells
DownloadSpring 2023
p53 transcriptional factor and tumor suppressor protein is mutated in over 50% of all cancers and most metastatic tumors. Majority of p53 mutations are single missense mutation and occur in the DNA-binding domain (DBD). The six most common missense mutations in the p53 DBD are known as “hot...
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Spring 2023
Introduction: Acute kidney injury (AKI) is associated with significant morbidity and mortality. It affects approximately 4 to 7% of hospitalizations each year with a reported annual increase of 10% in incidence. Many studies have relied on administrative diagnostic codes to describe temporal...
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Implementing and Evaluating Virtual Mindfulness-Based Stress Reduction for Adults with Inflammatory Bowel Disease
DownloadFall 2023
Inflammatory bowel diseases (IBD), which include Crohn’s disease and ulcerative colitis, are chronic diseases of the gastrointestinal tract. Individuals living with IBD suffer from chronic symptoms of fatigue and malnutrition and unpredictable flares of acute symptoms including abdominal pain,...
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The Development and Evaluation of a Frequently-Asked Question (FAQ) Answering Chatbot for an Online Mental Wellness Program for People with Chronic Disease
DownloadFall 2023
Introduction: Chatbots are computer programs that interact with humans through natural language conversations. Chatbots are on the rise due to numerous benefits like convenience, 24/7, personalized support, and they show promise in healthcare to support people living with chronic diseases. While...
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Automated Insulin Delivery System Use in Canada: Incorporating Perspectives of Both Users and Healthcare Providers
DownloadFall 2022
An Automated Insulin Delivery (AID) system combines an insulin pump and glucose sensor, with utilization of a computerized predictive algorithm, to enable automated adjustment in insulin delivery rate. Do-it-Yourself (DIY) or Open-source AID systems were the first form of this technology...
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The association between access to medical care (physicians and nurse practitioners) and impact on resident outcomes: A retrospective cross-sectional analysis
DownloadSpring 2022
The nursing home population is vulnerable and medically complex, yet little is known about models of medical service provision and associated quality outcomes. The goal of this thesis project is to examine the association between physician and nurse practitioner accessibility and practice...
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Fall 2022
Heart transplantation (HTx) is a life-saving intervention for patients with end-stage heart failure. Nonetheless, the development of Chronic Allograft Vasculopathy (CAV) limits the longevity of transplanted cardiac allografts and the survival of recipients. The pathogenesis of CAV begins with a...