Search
Skip to Search Results- 367Faculty of Pharmacy and Pharmaceutical Sciences
- 121Department of Biomedical Engineering
- 11Department of Medical Sciences
- 6Department of Electrical and Computer Engineering
- 5Department of Mechanical Engineering
- 4Faculty of Medicine
- 2Logan, Kerry Jane, 1955-
- 1AL Omair, Omar Abdulrahman
- 1AL-AGILI, MARWA
- 1Abbasi Dezfouli, Meysam
- 1Abdelmoneim, AS
- 1Abdulsalam Alharbi
- 15Pharmacokinetics
- 13MRI
- 8Cytochrome P450
- 7Cancer
- 6Magnetic Resonance Imaging
- 6Monoclonal antibodies
- 9Wilman, Alan (Biomedical Engineering)
- 8Beaulieu, Christian (Biomedical Engineering)
- 8El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6Thompson, Richard (Biomedical Engineering)
-
16R-HETE and 16S-HETE Alter Human Cytochrome P450 1B1 through Transcriptional and Allosteric Mechanism
DownloadFall 2022
Cardiac hypertrophy is a complex anomaly of the heart associated with increased muscle mass and thickening of the cell walls in response to accumulative stress. Although this condition occurs naturally, the prolonged state will progress into heart failure or even cause death. Recent studies have...
-
Fall 2020
This thesis describes the research and development process in creating a 3D ultrasound-based navigation system to assist screw insertion for scoliosis surgery, with a focus on children who have adolescent idiopathic scoliosis (AIS). Screw placement accuracy is critical to prevent spinal cord or...
-
4-aminobenzoic acid hydrazide mediated inhibition of Microperoxidase-11: catalytic inhibition by reactive metabolites.
DownloadFall 2011
Currently, there is lack of clinical therapeutics for inhibiting myeloperoxidase mediated pathogenesis. We used 4-aminobenzoic acid hydrazide (4-ABAH), the most potent irreversible inhibitor of myeloperoxidase and microperoxidase-11 to obtain mechanistic insight on the role of reactive...
-
A Combined Computational and Experimental Investigation of Polynucleotide Binding Polymers for Therapeutic Applications
DownloadFall 2017
Polynucleotide binding polymers have a wide range of therapeutic applications including delivery systems for therapeutic polynucleotides, and antithrombotic drugs for extracellular nucleic acid-mediated thrombogenic events. This dissertation explores polynucleotide binding polymers in these two...
-
Fall 2017
The voltage-gated KCNQ1/KCNE1 potassium ion channel plays a key role in maintaining the heart rhythm. An active channel generates the slow delayed rectifier (IKs) current in the heart. Both loss-of-function and gain-of-function mutations in KCNQ1 or KCNE1 are linked to many heart-related...