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Skip to Search Results- 340Department of Medicine
- 214Department of Medical Sciences
- 117Department of Biomedical Engineering
- 72Department of Public Health Sciences
- 16Department of Medical Genetics
- 12Department of Laboratory Medicine and Pathology
- 2Logus, J. Wayne (John Wayne), 1951-
- 1Abbasi Dezfouli, Meysam
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 1Acker, Jason Paul
- 13MRI
- 11Gene expression.
- 8DNA repair.
- 8Primary Biliary Cholangitis
- 7Copper. Physiological transport.
- 7Fibroblasts.
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Fall 2018
Background: Cancer-associated venous thromboembolism (VTE) is associated with significant morbidity and mortality. Cancer patients are at higher risk of VTE recurrence despite anticoagulation and bleeding complications while on anticoagulation. There are some risk factors of bleeding specific...
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Utility of Screening-Bead Assay in Testing for Formation of Donor-Specific Anti-HLA Antibodies and Antibody-Mediated Rejection in Renal Allografts Post-Transplant.
DownloadFall 2020
Background: Present-day immunosuppressive therapy in renal allograft recipients targets cell-mediated immunity and has significantly improved outcomes over the years. However, allograft failure rates still approach 50% towards 10 years post-transplantation. Antibody-mediated rejection (ABMR) is...
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Fall 2020
This thesis describes the research and development process in creating a 3D ultrasound-based navigation system to assist screw insertion for scoliosis surgery, with a focus on children who have adolescent idiopathic scoliosis (AIS). Screw placement accuracy is critical to prevent spinal cord or...
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A Combined Computational and Experimental Investigation of Polynucleotide Binding Polymers for Therapeutic Applications
DownloadFall 2017
Polynucleotide binding polymers have a wide range of therapeutic applications including delivery systems for therapeutic polynucleotides, and antithrombotic drugs for extracellular nucleic acid-mediated thrombogenic events. This dissertation explores polynucleotide binding polymers in these two...
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A Discrete Choice Experiment Pilot Study: Understanding Patient Preferences for In-centre Hemodialysis
DownloadFall 2021
Background: End-stage kidney disease (ESKD) is the failure of functioning kidneys such that they no longer have the capacity to sustain life without intervention. While the incidence of ESKD has remained generally stable across all ages of Canadians since 2000, the prevalence of ESKD has been...
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Spring 2013
Aims: This study aims to 1) provide a platform to discuss and document one First Nations community’s experiences and impacts of tuberculosis (TB); and 2) to understand the social context occurring within the community which may promote continual disease transmission. Methods: This Community-Based...
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Spring 2012
In Pulmonary Arterial Hypertension (PAH), pro-constrictive, pro-proliferative and anti-apoptotic diatheses converge to produce contraction and excessive proliferation of pulmonary artery smooth muscle cells (PASMC), a hallmark of PAH-vascular remodeling. The increased afterload causes right...
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A Novel 3D Printed Brace Manufacturing Process for the Treatment of Adolescent Idiopathic Scoliosis
DownloadSpring 2019
Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity with lateral curvature and axial vertebral rotation affecting 1-3% of adolescents. Bracing is a proven non-surgical treatment aiming to stop curve progression. Literature has shown that brace wear time affects brace...