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Skip to Search Results- 1Aderibigbe, Ayodeji O.
- 1Armanious, Gareth
- 1Augustine, Aruna M
- 1Bak, Jessi J.
- 1Ceholski, Delaine K
- 1Coccaro, Ersilia
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Sustained acidosis and phenylephrine activate the myocardial Na+/H+ exchanger through phosphorylation of Ser770 and Ser771
DownloadSpring 2010
The mammalian Na+/H+ exchanger isoform 1 (NHE1) is a ubiquitously expressed membrane protein that regulates myocardial intracellular pH. Inhibition of NHE1 prevents hypertrophy and reduces ischemia-reperfusion (I/R) injury in animal models. To understand the regulation of NHE1 in the myocardium...
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Fall 2016
The mammalian Na+/H+ exchanger isoform 1 (NHE1) is a ubiquitous plasma membrane protein that regulates intracellular pH by removing a proton in exchange for extracellular sodium. NHE1 is expressed in many tissues including the kidney where it has been demonstrated to play essential roles in pH...
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Fall 2013
Sodium proton exchangers (NHEs) are polytopic membrane proteins that, in archaea, bacteria, yeast and plants, provide increased salt tolerance by removing excess toxic sodium, and in mammals regulate cell volume, growth, differentiation, proliferation, migration and apoptosis in relation to...