This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Fall 2019
Heart failure (HF) is a condition where the cardiac muscle exhibits contractile dysfunction, limiting its ability to deliver adequate amounts of oxygen to organs throughout the body. Despite improved survival seen with pharmacological and mechanical treatment strategies, HF patients continue to...
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Cause of Death and the Impact of Implantable Cardioverter Defibrillators Among Patients with Diabetes Mellitus and Heart Failure
DownloadSpring 2020
Introduction: Diabetes and heart failure (HF) place a large burden on healthcare systems and are associated with increased risk for death, including sudden cardiac death (SCD). However, causes of death have not been fully explored and evidence for primary prevention...
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Fabry Cardiomyopathy and Heart Failure: The Roles of Inflammation and Valvular Heart Disease
DownloadSpring 2021
Fabry disease (FD) is an X-linked recessive multisystem disorder and an underrecognized secondary cause of hypertrophic cardiomyopathy. A gene variant encoding the enzyme α-galactosidase A results in deficient or absent hydrolase activity, resulting in the accumulation of glycosphingolipids in...
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Fall 2023
Heart failure is a condition whereby the weakened cardiac muscle can no longer pump blood to the rest of the body, resulting in decreased quality of life. Despite the severity of this debilitating condition, there is no cure for heart failure. Modulation of cardiac energy metabolism has become an...
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The Development and Evaluation of a Knowledge Translation Tool for Caregivers of Children with Heart Failure
DownloadFall 2024
Background: Having a child diagnosed with pediatric heart failure (PHF) is an anxiety-provoking experience for caregivers due to its high morbidity and mortality. PHF can follow a more chronic trajectory (e.g., cardiomyopathy, neuromuscular disease, myocarditis, etc.) when children who have...
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Use of Guideline-directed Medical Therapy in Patients ≥65 years after the Diagnosis of Heart Failure: A Canadian Population-based Study
DownloadFall 2023
Background: Guideline-directed medical therapy (GDMT) improves clinical outcomes in patients with heart failure (HF) with reduced ejection fraction (HFrEF). Despite proven efficacy, GDMT are under-utilized in clinical practice. The current study examines GDMT utilization after incident...