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Fall 2017
Kazemi Bajestani, Seyyed Mohammad Reza
Background: Cancer cachexia is referred to as a wasting condition, with skeletal muscle and fat loss. Although heart atrophy is recognized as a notable component of experimental cancer cachexia models, it has not been characterized in human studies. The contribution of cardiac structural and...
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Enhancing nutrition care in advanced pancreatic cancer: Defining clinical contributors to malnutrition progression and the impact of pancreatic enzyme replacement therapy
DownloadFall 2024
Introduction: Advanced pancreatic cancer (aPC) is an incurable disease in which palliative chemotherapy is offered to extend life. Most patients will experience cancer-associated malnutrition (CAM), marked by ongoing skeletal muscle loss and associated with poor survival and patient distress....
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Skeletal muscle in cancer: Exploration of the local immune environment and its associations to muscle mass in cancer
DownloadSpring 2020
Low muscle mass and muscle wasting are concerning issues as they are associated with poor outcomes and reduced survival in the oncological setting. Inflammation is a recognized contributor to disease-associated muscle loss; however, the biological characteristics of muscle tissue exhibiting...