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In silico and empirical analyses of the evolution and activity of diverse AB5 toxins found within the Salmonella genus
DownloadFall 2023
Bacterial AB5 toxins are secreted protein complexes composed of an enzymatic A subunit that disrupts host cell functions and a pentameric B subunit that facilitates cellular entry of the toxin by binding to specific cell surface receptors. AB5 toxins are widely recognized for their roles in the...
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Fall 2016
Bacteriophages are considered to be the most abundant and potentially the most diverse form of life on earth. Phage receptor binding proteins (RBPs), which allow phages to specifically target their host bacteria, consequently represent a massive diversity of bacterial targeting proteins. These...