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Skip to Search Results- 2Retinal Degeneration
- 1 Zebrafish
- 1Age-Related Macular Degeneration
- 1Animal Model
- 1Disease Models
- 1Docasahexaenoic Acid (DHA)
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Investigating Disease Presentation and Mechanism in RP1L1-Associated Photoreceptor Degeneration
DownloadFall 2021
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Retinitis pigmentosa 1-like 1 (RP1L1) is a component of the photoreceptor axoneme, the backbone structure of the photoreceptor’s light-sensing outer segment. Pathogenic variants...
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The Effects of Docosahexaenoic Acid (DHA) Dietary Supplementation in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3)
DownloadFall 2013
Underlying mechanisms of how docosahexaenoic acid (DHA) might impact the progression of macular degeneration are unknown. We relied on the ELOVL4 mouse model of juvenile macular degeneration, STGD3, to test the hypothesis that antenatal DHA dietary supplementation (2% w/w of total fatty acid)...