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Skip to Search Results- 1Bergeron, Amber
- 1Brachmann, Cole Garrett
- 1Conway, Jennifer
- 1Crisfield, Varina
- 1Lamarre, Jasmine JM
- 1Lambert, Jennifer E.
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Spring 2015
Background: Heart transplant is life-saving for children with end-stage congenital heart disease or acquired heart failure. Critical illness following transplantation can include acute kidney injury (AKI). There is little data on the epidemiology of, risk factors for, or impact on outcomes of...
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Characteristics of alpine plants and soils along an elevational gradient, Northern Selkirk Mountains, British Columbia
DownloadSpring 2019
Rates of climate change are accelerated at higher elevations, a pattern termed elevation-dependent warming (EDW). Consequently, the impacts of climate change on community patterning and soil development may be particularly evident in alpine environments. Alpine ecotone boundaries, such as...
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Estimating the Seroprevalence of Cytomegalovirus (CMV), Epstein-Barr Virus (EBV) and the Risk of Transfusion-Transmitted and Community-Acquired CMV Infection in Solid Organ Transplant Donors and Recipients
DownloadFall 2019
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are ubiquitous herpesviruses that establish lifelong, often asymptomatic, infections in healthy people, but are responsible for significant morbidity and mortality in certain hosts. CMV is the most common congenital infection worldwide, causing...
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Investigation of fatty acid and cholesterol synthesis using stable isotopes in type 1 diabetes, liver failure, islet and liver transplant, and effect of dietary intervention
DownloadSpring 2011
Elevated plasma lipids are risk factors for cardiovascular disease (CVD). In certain conditions plasma lipids are normal yet individuals experience increased morbidity. Type 1 diabetes (T1D) is associated with elevated CVD despite normal lipids, while in liver failure low plasma lipids may...
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Spring 2010
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of...
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Spring 2018
Climate change will continue to affect the Arctic more intensely than other biomes. These changes can have dramatic effects on biotic interactions that influence the functioning of these systems, including plant-herbivore interactions. Invertebrate herbivores strongly depend on external...
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Fall 2016
Background: NK cells are a key cellular component of antibody-mediated rejection (ABMR), but their role in ABMR has not been identified. We postulated that NK cells are stimulated through their CD16a antibody receptors by donor-specific anti-HLA antibodies in ABMR. There is currently no direct...
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Spring 2021
Mechanical circulatory support has become a therapeutic option for children with advanced heart failure. This type of support is often used to bridge patients to heart transplantation with approximately a third of all patients listed for transplant requiring some form of mechanical support. While...
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Proximal Impact of Transplant Tolerance-Promoting Antibody Therapies on Antigen-Specific T Cell Reactivity
DownloadFall 2013
The development of a transient, tolerance-promoting therapy is a critical goal in transplantation. Antibody-perturbation of T cell activation signals is considered a promising candidate. However, the mechanisms of such therapies remain vague. The lack of cohesive and systematic knowledge in the...
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Shrub encroachment in arctic and alpine tundra: Patterns of expansion and ecosystem impacts.
DownloadFall 2011
With a warming climate, northern ecosystems will face significant ecological changes such as permafrost thaw, increased frequency of forest fires, and shifting ecosystem boundaries including the spread of canopy-forming shrubs into tundra communities. A growing number of observations show...