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COUP-TF1 antagonizes Nkx25-mediated activation of the calreticulin gene during cardiac development
Download2001-01-01
Guo, Lei, Lynch, Jeffrey, Nakamur, Kimitoshi, Fliegel, Larry, Kasahara, Hideko, Izumo, Seigo, Komuro, Issei, Agellon, Luis B., Michalak, Marek
Calreticulin, a Ca2+ binding chaperone of the endoplasmic reticulum, is also highly expressed in the embryonic heart, and knockout of the calreticulin gene is lethal during embryogenesis because of impaired cardiac development. The protein is down-regulated after birth, and elevated expression of...
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High resolution optical tweezers for single molecule studies of hierarchical folding in the pbuE riboswitch aptamer
DownloadSpring 2010
Riboswitches are gene regulatory elements found in messenger RNA that function by changing structure upon the binding of a ligand to an aptamer domain. Single adenine-binding pbuE riboswitch aptamer RNAs were unfolded and refolded co-transcriptionally using optical tweezers for single molecule...
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Investigation of an enhancer-based regulation of LILRB1 gene and the differential functions of LILRB1 variants in natural killer cells
DownloadFall 2020
Human cytomegalovirus (HCMV) causes severe disease in immunocompromised people such as transplant patients. NK cells are crucial in controlling HCMV whereas HCMV developed multiple strategies to evade NK cell surveillance. HCMV encodes a human MHC-I homolog called UL18 to target an inhibitory...
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Making Feminism Popular: Audience Interpellation in Late Post-Network Era Television (a Case Study of TNT’s THE CLOSER)
DownloadSpring 2016
This dissertation explores the serial design model of The Closer. It answers the following question: How does The Closer offer multiple entry points along a spectrum of views on gender and feminism, appeal to a range of viewers, and thus secure popularity? To generate metadata of how The...
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Fall 2017
This study examines ways that both authoritarian capitalism and global flows of culture have shaped the Russian television industry. This dissertation explores three main questions: How does the system of state-directed capitalism shape television production, particularly with regards to...
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2006
Maynes, Warren, Mackey, Margaret
Using the example of the reconstructed history of one adolescent and his intense enthusiasm for the story Highlander (which is told in movies, novelizations, television programs and card games), this article explores questions of what we may and may not understand about what makes a story...
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New capitalization on old music: approaches to the use of Verdi's music in TV advertisements
DownloadSpring 2011
Advertisers use music in as much as 90% of television commercials. Classical and opera music play a special role in this medium, as classical music carries with it any number of already established inferences and meanings that may then be altered by the images in the commercial, or imparted upon...
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2014
Ruétalo, Victoria, Lacroix, Denis
The Nosotros television programme has existed in Edmonton, Alberta (Canada) since 1982 and has been broadcasting hour-long shows on Shaw Television. The programme, founded by Lito Azócar, represents the views, history and memory of local Latin American communities in Alberta. In keeping with its...