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Skip to Search Results- 1Abdul Rahman, Siti Aishah
- 1Ahrari, Malema
- 1Alles, Sascha R
- 1Chen, Yishen
- 1Dimopoulos, Ioannis
- 1Froentjes, Liesbeth
- 6Department of Pharmacology
- 6Department of Physiology
- 5Centre for Neuroscience
- 3Neuroscience
- 2Faculty of Nursing
- 1Department of Medicine
- 2Tse, Amy (Centre for Neuroscience and Department of Pharmacology)
- 1 Thomas Churchill (Department of Surgery)
- 1Al Hamarneh, Yazid (Pharmacology)
- 1Ali, Samina (Pediatrics and Emergency Medicine)
- 1Ballanyi, Klaus (Department of Physiology)
- 1Ballanyi, Klaus (Physiology Department, University of Alberta)
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Using EEG to examine inhibitory abilities in children: The effects of time pressure, physical activity, and emotion
DownloadFall 2018
The ability to inhibit inappropriate actions and irrelevant information is crucial for adaptive functioning. Inhibitory skills emerge early in life, with significant growth occurring during the period of early and middle childhood. The objective of this dissertation was to utilize...
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Fall 2015
Nucleosides are essential for RNA and DNA synthesis. They also play a central role in other cellular metabolic pathways, and modulate a diverse array of physiological processes, including renal and cardiovascular function and neurotransmission. Due to their hydrophilic nature, specialized...
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The Neonatal Locus Coeruleus is a Differentiated and Complex Neuromodulatory System as Revealed by Local Field Potential Analysis
DownloadSpring 2019
The locus coeruleus (LC) in the pons of the brainstem provides the sole source of noradrenergic afferent input to most brain structures including the cerebral cortex, hippocampus, cerebellum and spinal cord. The resulting modulation of activity is important for controlling behaviors like...
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The effect of long-term interleukin-1 beta exposure on sensory neuron electrical membrane properties: implications for neuropathic pain
DownloadSpring 2011
The effect of interleukin-1 beta (IL-1β) on the electrical properties of sensory neurons was assessed at comparable levels and exposure times to those found in animal models of neuropathic pain. Experiments involved whole cell current- or voltage-clamp recordings from rat dorsal root ganglion...
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Spring 2021
As one of the most accessible primary health care providers, pharmacists are in an excellent position to provide primary health care services. Although slow, the current transition from a dispensing-centered (transaction-based) pharmacy approach to a patient-centered (patient care based) approach...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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Short, Intermediate, and Long-Term Effects of Opioids on Pain Intensity in Patients with Osteoarthritis or Low Back Pain: A Systematic Review and Meta-Analysis
DownloadFall 2020
Chronic opioid use is associated with the development of hyperalgesia, which may end up attenuating any analgesic benefits over long-term therapy. We wanted to determine whether the analgesic efficacy of opioids compared to control therapy for osteoarthritis and chronic lower back pain differed...
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Regulation of Cardiac Gap Junctional Communication: Metabolic regulation of Cx40 and Cx43 via phosphorylation
DownloadFall 2015
Alterations in myocardial metabolism and cardiac electrophysiology associated with structural heart disease generate lethal arrhythmias. Differential levels of energy (ATP) supply and demand are generated with structural heart disease that is expected to activate 5’-amp activated protein kinase...
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Fall 2013
Glomus cells of the carotid body are peripheral chemoreceptors that detect changes in arterial oxygen levels. Hypoxia suppresses oxygen-sensitive K+ channels in glomus cells, resulting in cytosolic Ca2+ ([Ca2+]i) elevation in glomus cells via the activation of voltage-gated Ca2+ channels. The...