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Skip to Search Results- 3Peripheral Nerve Injury
- 1AlphaB-Crystallin
- 1Conditioning Electrical Stimulation
- 1Electrical Stimulation
- 1Macrophages
- 1Patient Perceived Barriers
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An Exploration of Severe Peripheral Nerve Injuries: Barriers to Timely Surgical Intervention
DownloadFall 2019
Introduction: The timing of nerve transfer or graft after peripheral nerve injury is critical, and accepted to be approximately 3 to 6 months. However, in practice, patients often present in a delayed manner for surgical intervention. This study describes the timing of surgery after peripheral...
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Investigating Mechanisms Responsible for the Pro-Regenerative Effects of Conditioning Electrical Stimulation
DownloadFall 2022
Though capable of regeneration, repair surgeries following peripheral nerve injury are often incomplete or entirely unsuccessful. The slow rate of regeneration (1-3mm/day) of a proximal injury requires up to two years to reach the distal target, whereas significant muscle atrophy occurs after...
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Investigating the Mechanism of Conditioning Electrical Stimulation: Identifying Key Parameters and Signaling Pathways
DownloadFall 2024
Despite timely surgical intervention, regeneration following peripheral nerve injury remains insufficient for adequate functional recovery. Thus, new therapeutic interventions are necessary. Traditionally, electrical stimulation has been delivered postoperatively to promote functional recovery...