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- 48Pediatrics
- 16Vaccinations
- 9Knowledge translation
- 6Primary care
- 6Quality improvement
- 55Graduate and Postdoctoral Studies (GPS), Faculty of
- 55Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 26Medicine and Dentistry, Faculty of
- 23Nursing, Faculty of
- 20Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 14Nursing, Faculty of/Health Systems
- 55Thesis
- 53Article (Published)
- 9Research Material
- 6Conference/Workshop Poster
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- 1Chapter
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The impact of bias on the magnitude of treatment effect estimates in oral health randomized trials
DownloadFall 2016
Background: There is emerging evidence that randomized trials are subject to biases. Flaws in the design of such trials can result in over- or underestimation of the treatment effect size. Aim: To examine the empirical evidence for bias, to quantify the extent of bias associated with methodology,...
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The pharmaceutical industry’s willingness-to-sell targeted chemotherapy for incurable solid cancers
DownloadSpring 2013
How the costs of research and its associated risks contribute to a minimum price that would support continued private pharmaceutical investment is unclear. We employed a linear cost-volume-revenue breakeven analysis to equate initial capital investment and risk, and its associated...
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The pot calling the kettle black: The extent and type of errors in a computerized immunization registry and by parent report.
Download2014
MacDonald, S., Golonka, R., Schopflocher, D.
Background Accurate classification of children’s immunization status is essential for clinical care, administration and evaluation of immunization programs, and vaccine program research. Computerized immunization registries have been proposed as a valuable alternative to provider paper records or...
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The Scope & Limits of Legal Intervention in Controversies Involving Biomedicine: A Legal History of Vaccination and English Law (1813–1853)
Download2011
This paper examines the historical role of law and politics in the adoption of smallpox vaccination in Britain, focusing primarily on the early Victorian period, when legislation was passed to enforce compulsory infantile vaccination. The primary thesis of the study is that law, and the processes...
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Fall 2017
Background: The use of long-term non-invasive ventilation (NIV), defined as the provision of respiratory support from the upper airway through a mask interface, has increased in infants and older children over the past two decades. A number of studies have been published on NIV use in the overall...
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The validity, reliability and time requirement of study model analysis using cone-beam computed tomography generated virtual study models
DownloadFall 2011
Objectives: To investigate the validity, reliability and time spent on performing a full orthodontic study model analysis (SMA) on Cone Beam Computed Tomography (CBCT)-generated dental models (Anatomodels) compared with conventional Plaster models and a subset of Extracted Premolars. Methods:...
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Fall 2016
Background. Tools and resources (TRs) can help to prevent obesity in children, particularly in settings that are accessible to families and well-aligned with chronic disease prevention, such as primary care. To date, little is known about the TRs that primary care providers (PCPs) currently use...
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Spring 2010
The increasing popularity of traditional Chinese medicine (TCM) therapies as health care options warrants thorough examination of the efficacy and safety evidence around these therapies. This thesis explores the intersection of TCM and fatigue using two rigorous methodologies: systematic reviews...
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Treatment in the pediatric emergency department is evidence based: a retrospective analysis.
Download2006
Wiebe, N., Waters, K. L., Cramer, K., Klassen, T. P., Hartling, L.
Background Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence for treatment provided in the PED comes from pediatric studies. Methods We...