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A Study of the Protein Phosphatase 1 (PP1) Regulatory Subunit, TIMAP, in Human Glomerular Endothelial Cells
DownloadFall 2015
TIMAP is a prenylated endothelial-predominant regulatory subunit for the serine/threonine (Ser,S/Thr,T) protein phosphatase 1 catalytic subunit (PP1c). TIMAP was first discovered in glomerular endothelial cells. It is expressed in the developing blood vessels of kidney, and its transcription in...
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Identification and characterization of sperm-specific components required for female meiosis in C. elegans
DownloadSpring 2022
In most sexually reproducing animals, sperm entry provides the signal to initiate the final stages of female meiosis. The molecular mechanism of this process is still unclear. In C. elegans, three maternally-expressed paralogs, memi-1, 2 and 3 (meiosis-to-mitosis) are required for sensing sperm...