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Skip to Search Results- 14Young, T. Kue
- 5Willows, Noreen D.
- 4Hegele, Robert A.
- 4Prado, Carla M.
- 4Proctor, Spencer D.
- 2Ban, Matthew R.
- 40Graduate and Postdoctoral Studies (GPS), Faculty of
- 40Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 17Agricultural, Food and Nutritional Science, Department of
- 17Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 16School of Public Health
- 16School of Public Health/Journal Articles (Public Health)
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Impact of a 3-year multi-centre community-based intervention on risk factors for chronic disease and obesity among free-living adults: the Healthy Alberta Communities study
Download2016-01-01
Lytvyak, E., Olstad, D. L., Schopflocher, D. P., Plotnikoff, R. C., Storey, K. E., Nykiforuk, Candace I.J., Raine, K. D.
Background: Healthy Alberta Communities (HAC) was a 3-year community-based intervention to reduce lifestyle-related risk factors for chronic disease and obesity at a population-level. The current paper examines changes in blood pressure (BP) and anthropometric indicators within HAC communities...
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Characterizing the Mesolimbic Dopamine Reward Pathway in a Magel2-null Mouse, a Model of Prader-Willi Syndrome
DownloadFall 2016
Prader-Willi Syndrome (PWS) is a genetic disorder characterized by extreme hyperphagia that can lead to severe obesity. The abnormal motivation to eat in PWS suggests a disruption in the hedonic feeding pathway, which is feeding based on reward as opposed to physiological need. Hedonic feeding is...
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Fall 2016
Adults with class II/III obesity (BMI ≥35 kg/m2) are at increased health risk, and may also present with lower lean mass in relation to excess adiposity, a condition termed sarcopenic obesity. A variety of body composition indices and cutpoints have been used to define this condition, mostly in...
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Fall 2016
Background. Tools and resources (TRs) can help to prevent obesity in children, particularly in settings that are accessible to families and well-aligned with chronic disease prevention, such as primary care. To date, little is known about the TRs that primary care providers (PCPs) currently use...
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Spring 2016
The prevalence of obesity worldwide has increased in the last few decades. The risk of obesity comes from its association with various clinical diseases especially cardiovascular diseases and diabetes. In this thesis, we assessed the expression of some drug metabolizing enzymes and transport...
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Cardiomyocyte antihypertrophic effect of adipocyte tissue conditioned medium from rats and its abrogation by obesity is mediated by the leptin to adiponectin ratio
Download2016
Karmazyn, Morris, Proctor, Spencer D., Mangat, Rabban, Gan, Xiaohong T., Bairwa, Suresh C., Rajapurohitam, Venkatesh
White adipocytes are known to function as endocrine organs by secreting a plethora of bioactive adipokines which can regulate cardiac function including the development of hypertrophy. We determined whether adipose tissue conditioned medium (ATCM) generated from the epididymal regions of normal...
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Sarcopenic obesity and myosteratosis are associated with higher mortality in patients with cirrhosis
Download2016
Beaumont, C., Angulo, P. Meza-Junco, J., Prado, C. M., Montano-Loza, A. J., Esfandiari, N., Sawyer, M. B., Ma, M., Baracos, V. E.
Background and aimsObesity is frequently associated with cirrhosis, and cirrhotic patients may develop simultaneous lossof skeletal muscle and gain of adipose tissue, culminating in the condition of sarcopenic obesity. Additionally, muscle depletionis characterized by both a reduction in muscle...
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Practical Considerations for Body Composition Assessment of Adults with Class II/III Obesity Using Bioelectrical Impedance Analysis or Dual-Energy X-Ray Absorptiometry
Download2016-09-03
Johnson Stoklossa, Carlene A., Forhan, Mary, Padwal, Raj S., Gonzalez, Maria Cristina, Prado, Carla M.
Purpose of Review The purpose of this review is to explore the practical considerations for body composition assessment of adults with class II/III obesity. Studies assessing adults (18–64 years) with a body mass index (BMI) ≥35 kg/m2 with bioelectrical impedance analysis (BIA) and/or dual-energy...
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Differential expression of hypothalamic metabolic and inflammatory genes in response to short-term calorie restriction in juvenile obese- and lean-prone JCR rats
Download2015
Vine, Donna F., Jacobs, Rene, Pierce, W.D., Heth, C.D., Russell, Jim, Proctor, Spencer D., Borthwick, Faye, Nelson, Randy, Diane, Abdoulaye, Mangat, Rabban
Background: Childhood obesity is an important early predictor of adult obesity and associated comorbidities. Common forms of obesity are underpinned by both environmental and genetic factors. However, the rising prevalence of obesity in genetically stable populations strongly suggests that...
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The Effects of Elements of Cardiometabolic Syndrome on Metformin Disposition: Obesity and Hyperlipidemia
DownloadFall 2015
The influences of obesity, Roux-en-Y gastric bypass bariatric (RYGB) surgery and hyperlipidemia on metformin pharmacokinetics (PK) were investigated. A sensitive and novel HPLC-UV reverse phase assay method was developed and utilized. Detection and mass characterization for metformin metabolites...