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Functional and Topological Analysis of Acyl-CoA:Diacylglycerol Acyltransferase 2 From Saccharomyces cerevisiae
DownloadSpring 2011
Acyl-CoA:diacylglycerol acyltransferase (EC 2.3.1.20, DGAT or DAGAT) is a membrane protein found mainly in the endoplasmic reticulum (ER). It catalyzes the final step in the biosynthesis of triacylglyerol (TAG or TG), which is the principal repository of fatty acids for energy utilization and...
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Structural and Functional Analysis of Intracellular Loop 5 of the NHE1 Isoform of the Na+/H+ Exchanger
DownloadFall 2017
The mammalian Na+/H+ exchanger isoform 1 (NHE1) is an integral membrane protein that regulates intracellular pH. It removes a single intracellular proton in exchange for one extracellular sodium ion. It has a large 500 amino acid N-terminal membrane domain that mediates transport and consists...