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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...
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The current recommended vitamin D intake guideline for diet and supplements during pregnancy is not adequate to achieve vitamin D sufficiency for most pregnant women
Download2016
Maggiore, Jack A., Eliasziw, Misha, Rabi, Doreen, O'Beirne, Maeve, Field, Catherine J., Hanley, David A., Dewey, Deborah, Aghajafari, Fariba, Weinberg, Amy, Kaplan, Bonnie J., Ross, Sue
Background The aims of this study were to determine if pregnant women consumed the recommended vitamin D through diet alone or through diet and supplements, and if they achieved the current reference range vitamin D status when their reported dietary intake met the current recommendations....
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Taxonomic assessment of rumen microbiota using total RNA and targeted amplicon sequencing approaches
Download2016
Janssen, Peter H., Li, Fuyong, Sun, Xu, Cox, Faith, Guan, Leluo, Henderson, Gemma
Taxonomic characterization of active gastrointestinal microbiota is essential to detect shifts in microbial communities and functions under various conditions. This study aimed to identify and quantify potentially active rumen microbiota using total RNA sequencing and to compare the outcomes of...
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Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
Download2015
Cox, Faith, Janssen, Peter H., Henderson, Gemma, Jonker, Arjan, Young, Wayne, Ganesh, Siva
Ruminant livestock are important sources of human food and global greenhouse gas emissions. Feed degradation and methane formation by ruminants rely on metabolic interactions between rumen microbes and affect ruminant productivity. Rumen and camelid foregut microbial community composition was...
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Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life
Download2014
Liang, Guanxiang, Bao, Hua, Guan, Leluo, Griebel, Philip J., Stothard, Paul, McFadden, Thomas B., Malmuthuge, Nilusha
This study aimed to investigate the potential regulatory role of miRNAs in the development of gastrointestinal tract (GIT) during the early life of dairy calves. Rumen and small intestinal (mid-jejunum and ileum) tissue samples were collected from newborn (30 min after birth; n = 3), 7-day-old...
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Letter to the Editor: Comment on 'Diet quality index as a predictor of treatment efficacy in overweight and obese adolescents: The EVASYON study'
Download2020-04-01
Orsso, Camila E., Ripka, Wagner L., Prado, Carla M.
Originally published in Clinical Nutrition: https://doi.org/10.1016/j.clnu.2020.02.010
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Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction
Download2012
Rang, Sara, Roos, Stefan, Phillipson, Mia, Holm, Lena, Dicksved, Johan, Willing, Ben P., Petersson, Joel, Schreiber, Olof
Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due to reduced P-selectin-dependent leukocyte- and platelet-endothelial cell interactions, however, the mechanism behind this protective...
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Genome wide identification and functional prediction of long non-coding RNAs responsive to Sclerotinia sclerotiorum infection in Brassica napus
Download2016
Rahman, Muhammad H., Megha, Swati, Joshi, Raj K., Basu, Urmila, Kav, Nat N. V.
Sclerotinia stem rot caused by Sclerotinia sclerotiorum affects canola production worldwide. Emerging evidence suggests that long non-coding RNAs (lncRNAs) play important roles in the regulation of gene expression in plants, in response to both abiotic and biotic stress. So far, identification of...
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Elucidation of molecular mechanisms of physiological variations between bovine subcutaneous and visceral fat depots under different nutritional regimes
Download2013
Jin, Weiwu, He, Maolong, Guan, Leluo, Romao, Josue M., McAllister, Tim
Adipose tissue plays a critical role in energy homeostasis and metabolism. There is sparse understanding of the molecular regulation at the protein level of bovine adipose tissues, especially within different fat depots under different nutritional regimes. The objective of this study was to...
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Differential expression of miRNAs in Brassica napus root following infection with Plasmodiophora brassicae
Download2014
Basu, Urmila, Verma, Shiv, Rahman, Muhammad H., Deyholos, Michael K., Kav, Nat N. V.
Canola (oilseed rape, Brassica napus L.) is susceptible to infection by the biotrophic protist Plasmodiophora brassicae, the causal agent of clubroot. To understand the roles of microRNAs (miRNAs) during the post-transcriptional regulation of disease initiation and progression, we have...